外周T细胞淋巴瘤常表达αβTCR ,只有少数表达γδTCR。由γδT细胞肿瘤性增生所形成的T细胞肿瘤称为γδT细胞淋巴瘤 ,最具代表性是肝脾γδT细胞淋巴瘤 ,瘤细胞累及肝脾、骨髓 ,呈窦内侵犯 ;大多数表达CD4 CD8 ,可表达NK细胞相关抗原及细胞毒淋巴细胞标记 ;遗传学上可检测到 7号染色体异常i(7q)。发生于结外 ,如皮肤、消化道、呼吸道的γδT细胞淋巴瘤以及发生于淋巴结的γδT细胞淋巴瘤都有其特殊临床病理学特征。 Peripheral T cell lymphoma often expresses αβTCR, only a few express γδTCR. The T cell tumor formed by the γδ T cell tumor proliferation is called γδ T cell lymphoma, the most representative is the liver and spleen γδ T cell lymphoma. The tumor cells involve the liver, spleen and bone marrow, Can express NK cell-associated antigen and cytotoxic lymphocyte markers; genetically detectable chromosome 7 abnormal i (7q). Occurred in the extranodal, such as skin, gastrointestinal tract, respiratory γδ T cell lymphoma and lymph node in the γδ T cell lymphoma has its own special clinicopathological features.