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目的比较卡维地洛治疗维吾尔族与汉族扩张型心肌病心力衰竭的临床疗效。方法扩张型心肌病患者41例,其中维吾尔族22例,汉族19例,维吾尔族组心功能Ⅱ级9例,Ⅲ级10例,Ⅳ级3例;汉族组心功能Ⅱ级6例,Ⅲ级7例,Ⅳ级6例。均于慢性心功能不全基础治疗上加用卡维地洛。治疗6个月观察其疗效。结果维吾尔族组有效率95.46%,汉族组有效率94.74%。左室射血分数(LVEF)的改善汉族组略优于维吾尔族组,而左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)的改善两组无明显差异(P<0.01)。结论卡维地洛可显著改善心功能,明显提高扩张型心肌病患者生活质量,在新疆维吾尔族与汉族扩张型心肌病患者中应用无明显疗效差异。
Objective To compare the clinical efficacy of carvedilol in the treatment of heart failure with Uygur and Han dilated cardiomyopathy. Methods Twenty-one patients with dilated cardiomyopathy were enrolled, including 22 Uyghur nationality, 19 Han nationality, 9 Uygur group, 9 Uygur group, 10 Uygur group, 3 Uygur group, 6 Uygur group, 6 Uygur group, 7 cases, Ⅳ grade in 6 cases. All in the basic treatment of chronic heart failure plus carvedilol. Treatment for 6 months to observe its efficacy. Results The Uygur group was 95.46%, while the Han group was 94.74%. Left ventricular ejection fraction (LVEF) improvement in the Han group slightly better than the Uygur group, and left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD) improvement in the two groups was no significant difference (P <0.01). Conclusion Carvedilol can significantly improve cardiac function and significantly improve the quality of life of patients with dilated cardiomyopathy. There is no significant difference in the therapeutic effect between Uygur and Han patients with dilated cardiomyopathy in Xinjiang.