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目的:评价聚乙二醇4000预防化疗过程中便秘的效果。方法:按入选标准抽取115例化疗并同时使用5-HT3受体阻滞剂的病人,随机分为实验组55人,对照组60人。实验组化疗同时口服聚乙二醇4000,每日2次,每次10克,两组病人同样接受饮食健康指导。结果:实验组便秘的发生程度及发生率明显低于对照组(z=-3．86,P=0．000;x2=13．66, P<0．01)。结论:聚乙二醇4000是预防化疗过程中便秘的有效安全的药物。
Objective: To evaluate the effect of polyethylene glycol 4000 in preventing constipation during chemotherapy. Methods: According to the selected criteria, 115 patients with chemotherapy and 5-HT3 blockers were randomly divided into experimental group (55) and control group (60). Experimental group also received oral polyethylene glycol 4000, 2 times a day, each 10 grams, two groups of patients also receive diet health guidance. Results: The incidence and incidence of constipation in the experimental group were significantly lower than those in the control group (z = -3.86, P = 0.000; x2 = 13.66, P <0.01). Conclusion: Polyethylene glycol 4000 is an effective and safe drug for preventing constipation during chemotherapy.