妊娠期甲状腺激素的合成、分泌及代谢发生相应的改变,妊娠合并甲状腺功能减退症(简称甲减)导致流产、早产、妊娠期高血压疾病及妊娠期糖代谢异常等产科并发症的发生率增加,并可能影响后代的智力发育。对确诊临床甲减的妊娠期妇女早期给予左旋甲状腺素(L-T4)治疗能改善妊娠结局。 Pregnancy thyroid hormone synthesis, secretion and metabolism of the corresponding changes in pregnancy associated with hypothyroidism (referred to as hypothyroidism) led to miscarriage, premature birth, gestational hypertension and gestational glucose metabolism abnormalities such as the incidence of obstetric complications increased , And may affect the intellectual development of future generations. Early conception of clinical hypothyroidism in pregnant women given levothyroxine (L-T4) early treatment can improve pregnancy outcomes.