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目的:观察蝉衣莱菔汤加减联合西药治疗肝硬化顽固性腹水疗效。方法:选取我院2012年1月~2015年5月收治81例肝硬化顽固性腹水患者作为研究对象,随机数字表法分为治疗组(n=41)与对照组(n=40)。对照组常规止血、扩容、护肝基础上应用奥曲肽治疗,观察组在对照组基础上联用蝉衣莱菔汤,比较两组治疗总有效率、腹水消退良好率、药物安全性。结果:观察组治疗有效率92.7%,高于对照组75.0%,比较有统计学意义(P<0.05)。治疗组腹水消退良好率达95.1%,明显高于对照组80.0%,比较有统计学意义(P<0.05)。两组安全分级平均值的比较无统计学意义(P>0.05),且均为1级左右,提示均具有较高安全性。结论:蝉衣莱菔汤加减联合西药治疗肝硬化顽固性腹水可发挥行气利水、消肿利湿之功,促进腹水的消退,且具有较高安全性,效果显著,临床借鉴、推广较高。
Objective: To observe the curative effect of the treatment of refractory ascites due to cirrhosis of the liver with the treatment of Chan Yi Lai 菔 Decoction combined with Western medicine. Methods: A total of 81 patients with cirrhosis and refractory ascites admitted to our hospital from January 2012 to May 2015 were selected and divided into treatment group (n = 41) and control group (n = 40). Control group conventional hemostasis, dilatation, liver based on the application of octreotide treatment, the observation group in the control group based on the Chan Yi Lai Tang, the two groups were compared the total effective rate, good rate of ascites regression, drug safety. Results: The effective rate of the observation group was 92.7%, higher than that of the control group (75.0%), with statistical significance (P <0.05). The rate of ascites subsided in the treatment group was 95.1%, which was significantly higher than that in the control group (80.0%, P <0.05). There was no significant difference between the two groups (P> 0.05), and they were all about grade 1, suggesting that they all had higher safety. Conclusion: Modified Zhuji Decoction combined with western medicine in the treatment of refractory ascites of liver cirrhosis can exert the effects of qi and water, swelling and dampness, promote the regression of ascites, and has high safety, the effect is remarkable, clinical reference and promotion are higher.