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目的:探讨腹部CT在克罗恩病(CD)诊断和治疗中的价值。方法:回顾性分析2001年1月至2011年6月中国医科大学附属盛京医院62例确诊为CD的患者的临床资料,分别对腹部CT、口服法小肠造影(SBFT)及结肠镜3种检查方法在诊断CD时完成情况、肠内外病变及并发症的诊断情况进行比较分析。结果:62例患者中,44例完成结肠镜(71.0%)、39例完成了SBFT(62.9%)、59例完成了CT(95.2%)。节段性病变检出率分别为:结肠镜11.4%(5/44),SBFT 28.2%(11/39),CT 54.2%(32/59),P<0.05;对结肠及末段回肠病变检出率比较,CT 85.7%(38/42),结肠镜68.2%(30/44),P<0.05;对小肠病变检出率比较,CT84.2%(32/38),SBFT59.0%(23/39),P<0.05。与SBFT相比,CT在对CD并发症诊断方面具有优势,但其差异无统计学意义(P>0.05)。结论:CT对于跳跃性病变,肠壁本身及肠外病变方面有独特的优势,在CD的诊断和治疗中具有很大的价值。
Objective: To investigate the value of abdominal CT in the diagnosis and treatment of Crohn’s disease (CD). Methods: The clinical data of 62 patients diagnosed with CD from Shengjing Hospital Affiliated to China Medical University from January 2001 to June 2011 were retrospectively analyzed. Three kinds of examinations including abdominal CT, oral small bowel imaging (SBFT) and colonoscopy Methods The diagnosis of CD was completed, the pathological changes of internal and external organs and the complications were analyzed comparatively. RESULTS: Of 62 patients, 44 completed colonoscopy (71.0%), 39 completed SBFT (62.9%), and 59 completed CT (95.2%). The detection rates of segmental lesions were: colonoscopy 11.4% (5/44), SBFT 28.2% (11/39), CT 54.2% (32/59), P <0.05; CT 85.7% (38/42), colonoscopy 68.2% (30/44), P <0.05; the detection rate of small intestine lesions, CT84.2% (32/38), SBFT59.0% 23/39), P <0.05. Compared with SBFT, CT has the advantage in the diagnosis of CD complications, but the difference was not statistically significant (P> 0.05). Conclusion: CT has unique advantages in leapfrog disease, intestinal wall itself and extraintestinal disease, and is of great value in the diagnosis and treatment of CD.