我们对确诊为肾病综合征(NS)13例患者,应用抗凝、免疫抑制剂、激素、对症等方法治疗效果不佳或困难者,临床表现高度浮肿,有大量腹水时,采用腹水环注治疗,取得了明显疗效。报告如下。 一般资料 13例患者,男性12例,女性1例。年龄15～65岁,平均36岁。均符合NS诊断标准,临床表现高度浮肿,有胸水及大量腹水,其中原发性NS10例,继发NS3例。伴肾功能不全12例。 方法 (1)采用瑞典Gambro公司生产的AK-10血液滤过机,FH202或FH77型聚胺脂膜空心纤维过滤器,膜孔径4～4.5DW,聚乙烯动静脉导管及超滤管。(2)穿刺点:脐与左髂前上棘连线1/2交界处向上或向下2cm处。穿刺针经皮穿透腹膜后将针芯稍后退,再将针送入腹腔,把针蕊拔出连接动脉导管引出腹水,通过滤器。流量70～200ml/min,负压70～150。回输针自右上腹脐旁3cm处刺入腹腔。腹水浓缩后回输腹 We diagnosed nephrotic syndrome (NS) in 13 patients, the application of anticoagulants, immunosuppressive agents, hormones, symptomatic and other methods to treat poor or difficult, highly edema clinical manifestations, a large number of ascites, the use of ascites annuli treatment , Made a significant effect. The report is as follows. General information 13 patients, 12 males and 1 female. Aged 15 to 65 years old, average 36 years old. All were consistent with NS diagnostic criteria, the clinical manifestations of highly edema, pleural effusion and a large number of ascites, including primary NS10 cases, secondary NS3 cases. With renal insufficiency in 12 cases. Methods (1) AK-10 hemofilter, FH202 or FH77 type hollow fiber membrane filter made by Gambro Company of Sweden, membrane diameter 4 ~ 4.5DW, polyethylene vein catheter and ultrafiltration tube were used. (2) puncture point: navel and left anterior superior iliac spine connection 1/2 junction up or down 2cm Department. Percutaneous puncture through the peritoneum after the needle core retreat later, then the needle into the abdominal cavity, the needle core pull out the connection of the arterial catheter leads to ascites, through the filter. Flow 70 ~ 200ml / min, negative pressure 70 ~ 150. Back to the needle from the right upper quadrant of the umbilical 3cm puncture the abdominal cavity. Ascites concentrated back to the back of the belly