脑胶质瘤是颅内最常见的原发性恶性肿瘤,胶质瘤呈浸润性生长。肿瘤与正常脑组织之间边界模糊,手术时只能根据经验判断切除程度。如果切除少了会残留微小病灶,导致肿瘤复发;切除过多了会损伤脑功能区,造成失语、瘫痪等严重后遗症。复旦大学药学院与附属华山医院合作开发一种对肿瘤酸性环境具有双模态信号响应的金纳米粒影像探 Glioma is the most common primary intracranial malignancy, glioma was invasive growth. The boundary between the tumor and the normal brain is blurred. The degree of resection can only be judged according to the experience when the operation is performed. If less resection will remain tiny lesions, resulting in tumor recurrence; too much resection can damage brain function areas, resulting in aphasia, paralysis and other serious complications. Fudan University School of Medicine and affiliated Huashan Hospital to develop a dual-mode signal response to tumor acidic environment gold nanoparticles imaging