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目的了解延安市实施口服脊髓灰质炎(脊灰)疫苗(OPV)强化免疫活动以来,健康人群脊灰抗体水平。方法随机抽样确定安塞县0~39岁人群269名,采集血清标本,检测脊灰抗体。结果脊灰Ⅰ、Ⅱ、Ⅲ型中和抗体阳性率分别为94.05%、97.40%、86.25%,几何平均滴度分别为1∶172.59、1∶90.39、1∶36.49。结论延安市通过OPV常规免疫和强化免疫后,健康人群对脊灰已形成免疫屏障。
Objective To understand the level of poliovirus antibodies in healthy population since the implementation of oral poliovirus (OPV) boosting in Yan’an. Methods A total of 269 people aged 0-39 years in Ansai County were collected by random sampling. Serum samples were collected to detect the antibodies against polio. Results The positive rates of neutralizing antibodies of type Ⅰ, Ⅱ and Ⅲ were 94.05%, 97.40% and 86.25%, respectively. The geometric mean titers were 1:172.59, 1:90.39 and 1:36.49 respectively. Conclusions After normal and OPV immunization of OPV in Yan’an City, healthy people have formed an immune barrier to polio.