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目的观察低分子肝素钙针、奥扎格雷钠针联合应用对急性脑梗死的疗效。方法将194例诊断明确的急性脑梗死患者随机分成2组:治疗组97例,低分子肝素钙针5000U,皮下注射,1次/12h,连用7d;奥扎格雷钠针80mg溶于250ml生理盐水静滴,1次/d,连用14d。对照组血塞通10ml溶于250ml5%葡萄糖液中静滴,1次/d,连用14d。按临床神经功能缺损程度评分标准于治疗后14d进行疗效评定。结果治疗组总有效率96.9%和显效率77.2%,与对照组比较有显著性差异(P<0.05)。结论低分子肝素钙、奥扎格雷钠联合治疗急性脑梗死,临床观察疗效满意,且无明显不良反应。
Objective To observe the curative effect of low molecular heparin calcium needle and ozagrel sodium needle on acute cerebral infarction. Methods One hundred and ninety-four patients with acute cerebral infarction were randomly divided into two groups: 97 cases in the treatment group, 5000U in low molecular weight heparin, 7 days in subcutaneous injection for 1/12 hours, and 80 mg of ozagrel sodium in 250 ml of normal saline Intravenous infusion, 1 time / d, once every 14d. The control group Xuesaitong 10ml dissolved in 250ml5% glucose solution intravenous infusion, 1 / d, once every 14d. According to the clinical neurological deficit score standard 14d after treatment efficacy evaluation. Results The total effective rate was 96.9% and the effective rate was 77.2% in the treatment group, which was significantly different from the control group (P <0.05). Conclusion Low molecular weight heparin and ozagrel sodium combined with acute cerebral infarction are effective in clinical observation and have no obvious adverse reactions.