作者综述文献79篇详细介绍了眼科应用色甘酸钠的药效学、药动学、临床观察及使用。色甘酸钠可以稳定肥大细胞膜,在细胞表面抗原抗体发生反应后可阻止组织胺及其它生化介质的释放。由于色甘酸钠脂溶性很差,故人眼局部给药后,全身吸收仅约0.03%,然后以原形从胆汁和尿中排出。色甘酸钠主要对Ⅰ型 The authors reviewed 79 articles describing the pharmacodynamics, pharmacokinetics, clinical observation and use of cromolyn sodium in ophthalmology. Cromolyn can stabilize the mast cell membrane and block the release of histamine and other biochemical mediators after the antigen on the cell surface has reacted. Due to the poor solubility of cromolyn sodium fat, so the human eye local administration, systemic absorption of only about 0.03%, and then the prototype from the bile and urine excretion. Main color cromolyn type I