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目的:分析≥50岁MSM的HIV感染状况及其相关因素，为制定有效的干预策略和措施提供参考。方法:采用方便抽样法，利用同性社交软件Blued 7.1.6进行问卷调查，收集调查对象社会人口学、行为学及自报HIV感染状态等信息。对自报HIV感染相关因素进行单因素n χ2检验和多因素logistic回归分析。n 结果:714例≥50岁MSM研究对象中，自报HIV感染率为17.6%（126/714）。自报HIV感染风险的多因素分析结果显示，离异/丧偶者是已婚者的2.07倍（95%n CI：1.34~3.21）；HIV相关知识不知晓者是知晓者的1.92倍（95%n CI：1.21~3.04）；有STD感染史者是无STD感染史者的3.17倍（95%n CI：2.09~4.83）。n 结论:≥50岁MSM的自报HIV感染率处于较高水平，离异/丧偶、HIV相关知识知晓率低、STD感染史等为自报HIV感染的相关因素。“,”Objectives:To explore the HIV prevalence and related factors among MSM aged 50 and above and provide evidence on the prevention and control of HIV/AIDS.Methods:Based on an MSM social application software Blued 7.1.6, we recruited participants through online convenience sampling to collect demographic variables, behavioral and self-reported HIV infection status, n etc. Univariate n χ2 test and multivariate logistic regression were used to analyze the related factors of self-reported HIV infection.n Results:Self-reported HIV infection rate was 17.6%(126/714) among the participants. In multivariable analysis, participants who got divorced or widowed had a 2.07(95%n CI: 1.34-3.21) times greater risk of self-reported HIV-positive than those who were married. Participants unaware of HIV-related knowledge showed a 1.92(95%n CI:1.21-3.04) times greater risk of self-reported HIV-positive than those with better HIV-related knowledge. Participants who have ever been diagnosed with sexually transmitted disease (STD) showed a 3.17(95%n CI:2.09-4.83) times greater risk of self-reported HIV-positive than those without STD infection history.n Conclusion:Our findings indicated that the self-reported HIV infection rate was high among MSM aged 50 and above. Being divorced or widowed, being unaware of HIV-related knowledge and STD infection history was proved related with self-reported HIV infection.