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胃肠道间质瘤(GISTs)是存在于胃肠道间叶组织的肿瘤,在消化道间叶肿瘤中占大部分,是间叶组织产生的肿瘤,胃肠道平滑肌肉瘤或胃肠道平滑肌瘤。在临床病理诊断中,胃肠道间质瘤只占胃肠道间叶性肿瘤的一少部分。CD117、CD34、Ki-67和DOG1都是用于诊断胃肠道间质瘤的标志物。本文主要探讨的是CD17、CD34、Ki-67和DOG1在胃肠道间质瘤中的表达及临床意义。
Gastrointestinal stromal tumors (GISTs) are tumors that exist in the gastrointestinal mesenchymal tissue and predominate in gastrointestinal metaphase and are tumors of mesenchymal tissue, gastrointestinal leiomyosarcoma or gastrointestinal tract smooth Fibroids. In the clinicopathological diagnosis, gastrointestinal stromal tumors only account for a small part of gastrointestinal mesenchymal tumors. CD117, CD34, Ki-67 and DOG1 are both markers for the diagnosis of gastrointestinal stromal tumors. This article focuses on the expression of CD17, CD34, Ki-67 and DOG1 in gastrointestinal stromal tumors and its clinical significance.