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发生在皮肤的B细胞淋巴瘤及少数T细胞淋巴瘤镜下见肿瘤细胞可显示梭形细胞样特征,目前有关皮肤梭形细胞样B细胞淋巴瘤(c SCBCLs)报道不足30例,既往c SCBCLs常被归为变异亚型的弥漫大B细胞淋巴瘤(DLBCL),因而有学者认为其比同类B细胞淋巴瘤更具侵袭性而需接受强化治疗。作者报道了据认为是迄今为止最大宗的一组c SCBCLs病例的临床病理特点及免疫组化特征,24例患者中男性18例,女性6例,年龄27~88岁,平均55岁;多数发生于头部(12/24)、躯干(8/24)及下肢(4/24)皮肤;所有病例组织形态学相似,大体表现为红色或棕红色丘疹样结节,镜
Occurred in the skin of B cell lymphoma and a small number of T-cell lymphoma see tumor cells can show spindle cell-like features, the current skin spindle cell-like B-cell lymphoma (c SCBCLs) reported less than 30 cases of previous c SCBCLs Often classified as a variant subtype of diffuse large B cell lymphoma (DLBCL), so some scholars believe that it is more aggressive than similar B-cell lymphoma and need intensive treatment. The authors report the clinicopathological features and immunohistochemical characteristics of a group of c SCBCLs that are believed to be by far the largest. 18 of 24 patients had males and 6 females, with a mean age of 55 years, ranging from 27 to 88 years; the majority occurred In the head (12/24), trunk (8/24) and lower extremity (4/24) skin; all cases histological similarities, generally showed red or reddish papules nodules, mirror