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目的 比较胰岛素泵持续皮下胰岛素输注 (CSII)法和传统的多次皮下注射胰岛素治疗法对 1型和 2型糖尿病的短期疗效。方法 糖尿病病人 48例 ( 1型糖尿病 14例 ,2型糖尿病人 3 4例 ) ,随机分为CSII组和对照组 ,CSII组予胰岛素泵持续皮下注射短效诺和灵 ,对照组于三餐前皮下注射短效诺和灵和睡前注射中效诺和灵。结果 两组达到相同的血糖水平 ,CSII组所需的治疗时间、胰岛素用量以及低血糖发生率明显减少 (P <0 0 5 )。结论 胰岛素泵强化治疗能更有效的模拟生理胰岛素的分泌 ,更快、更有效的控制高血糖 ,减少血糖波动和低血糖的发生
Objective To compare the short-term efficacy of insulin pump continuous subcutaneous insulin infusion (CSII) and conventional multiple subcutaneous insulin injections for type 1 and type 2 diabetes mellitus. Methods 48 patients with type 1 diabetes mellitus (14 type 1 diabetes and 34 type 2 diabetes mellitus) were randomly divided into CSII group and control group. In CSII group, short-acting norepinephrine was administered subcutaneously with insulin pump, while in control group, Subcutaneous injection of short-acting nocturnal and prenatal injection of norolide. Results The same blood glucose level was achieved in both groups, and the time required for treatment, the amount of insulin, and the incidence of hypoglycemia in the CSII group were significantly reduced (P <0.05). Conclusion Insulin pump intensive treatment can more effectively simulate the secretion of physiological insulin, faster and more effective control of hyperglycemia, reduce blood sugar fluctuations and hypoglycemia