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目的 研究B超引导下经皮肝穿刺注射无水乙醇 (percutaneousethanolinjection ,PEI)配合肝动脉化疗栓塞术 (transcatheterhepaticarterialchemoembolization ,TACE)治疗原发性肝癌的疗效。方法 原发性肝癌 87例 ,其中TACE组 45例 ,TACE +PEI组 42例。结果 TACE组 1,2 ,3年生存率分别为 6 6 .7%、41.2 %和 2 1.4% ,组织学检查仅 2 6 .1%的病变完全坏死 ;TACE +PEI组 1,2 ,3年生存率分别为 97.1%、85 .7%和 6 5 .7% ,组织学检查 81.8%的病变完全坏死。两组间在生存率和肿瘤完全坏死率间差异均有显著性 (P <0 .0 5 )。结论 对于原发性肝癌 ,TACE +PEI疗效优于单纯TACE ,是一种较好的综合治疗方法。
Objective To study the efficacy of transcutaneous hepatic injection of percutaneous ethanol injection (PEI) and transcatheter hepatic arterial chemoembolization (TACE) in the treatment of primary liver cancer. Methods Primary liver cancer was performed in 87 cases, including 45 patients in the TACE group and 42 patients in the TACE + PEI group. Results The 1-, 2-, and 3-year survival rates in the TACE group were 66.7%, 41.2%, and 21.4%, respectively. Histological examination showed that only 26.1% of the lesions were completely necrotic; TACE + PEI group 1, 2, and 3 years The survival rates were 97.1%, 85.7%, and 65.7%, respectively, and 81.8% of histological examinations were completely necrotic. There was a significant difference between the two groups in survival rate and complete necrosis rate (P < 0.05). Conclusion For primary liver cancer, TACE +PEI is superior to TACE alone and is a better comprehensive treatment.