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目的探讨硫辛酸联合疏血通治疗糖尿病周围神经病变的临床疗效。方法 90例糖尿病周围神经病变患者,随机分为观察组和对照组,各45例。对照组给予疏血通治疗,观察组给予硫辛酸联合疏血通治疗,评价疗效。结果观察组显效23例,有效21例,无效1例,治疗总有效率为97.8%;对照组显效19例,有效14例,无效12例,总有效率为73.3%;观察组治疗总有效率显著高于对照组,差异有统计学意义(P<0.05)。观察组治疗后震动感觉阈值低于治疗前,且低于对照组,差异有统计学意义(P<0.05);对照组治疗前后震动感觉阈值比较差异无统计学意义(P>0.05)。两组患者治疗中均未出现任何不良反应。结论采用硫辛酸联合疏血通治疗糖尿病周围神经病变,治疗效果显著,值得临床广泛推广应用。
Objective To investigate the clinical efficacy of lipoic acid combined with Shuxuetong in the treatment of diabetic peripheral neuropathy. Methods 90 patients with diabetic peripheral neuropathy were randomly divided into observation group and control group, 45 cases in each group. The control group was given Shuxuetong treatment. The observation group was given lipoic acid combined with Shuxuetong treatment to evaluate the curative effect. Results The observation group was effective in 23 cases, effective in 21 cases, ineffective in 1 case, the total effective rate was 97.8%; the control group markedly effective in 19 cases, effective in 14 cases, ineffective in 12 cases, the total effective rate was 73.3%; observation group the total effective rate Significantly higher than that of the control group, the difference was statistically significant (P <0.05). The threshold of sensation of vibration in the observation group was lower than that before treatment and lower than that in the control group (P <0.05). There was no significant difference in the sensory threshold before and after treatment in the control group (P> 0.05). No adverse reactions occurred in both groups. Conclusion Lipoic acid combined with Shuxuetong diabetic peripheral neuropathy, the treatment effect is significant, it is widely used in clinical practice.