论文部分内容阅读
目的了解医院住院患者念珠菌感染动态变化及其耐药性,为有效控制念珠菌感染提供参考。方法采用回顾性调查方法,对某医院2009-2011年住院患者感染标本念珠菌检出情况进行调查,并进行药敏试验结果分析。结果调查期间该医院共送检病原学标本11 378份,检出念珠菌1 407株,分离率为12.4%。2011年与2009年相比,念珠菌分离率上升了1.9%。以深部念珠菌感染为主,下呼吸道念珠菌感染占79.9%,其中白色念珠菌感染占70.8%。临床分离的念珠菌除对两性霉素B比较敏感之外,对其他4种抗真菌药物均存在不同程度的耐药性。结论该医院住院患者感染标本念珠菌分离率呈现逐年增加趋势,白色念珠菌是感染的优势菌株,提示应重视临床念珠菌感染的防控。
Objective To understand the dynamic changes and drug resistance of Candida albicans in hospitalized inpatients and provide references for the effective control of Candida infection. Methods A retrospective survey was conducted to investigate the detection of Candida in hospitalized patients from 2009 to 2011 in a hospital and the result of drug susceptibility test was analyzed. Results During the investigation, 11 378 specimens of pathogenic bacteria were collected from the hospital, and 1 407 strains of Candida were detected with a separation rate of 12.4%. Candida isolates rose 1.9% in 2011 compared with 2009. Candida deep infection, lower respiratory tract Candida infection accounted for 79.9%, of which Candida albicans infection accounted for 70.8%. In addition to the clinical isolates of Candida amphotericin B more sensitive to the other four anti-fungal drugs have varying degrees of resistance. Conclusion Candida isolates from hospitalized patients showed a trend of increasing year by year. Candida albicans was the predominant strain of infection, suggesting that prevention and control of clinical candidiasis should be emphasized.