卵巢癌是妇科三大恶性肿瘤的一种,其死亡率居第一位,严重危害妇女的健康。卵巢癌具有起病隐匿、侵袭性强、转移快、预后差等特点,尤其是卵巢上皮性癌,发现时多数已是晚期,使患者错过了最佳治疗时机。因此,早发现、早治疗成为减低卵巢癌死亡率的最好办法,早期发现的卵巢癌手术后的5年生存率可达95%。一直以来,寻找能帮助早期诊断卵巢癌的肿瘤标志物成为临床工作的重点。 Ovarian cancer is one of the three major gynecological malignancies, with the highest mortality rate and seriously endangering women’s health. Ovarian cancer with occult onset, aggressive, fast transfer, poor prognosis and other characteristics, especially epithelial ovarian cancer, found that most are late, so that patients missed the best timing of treatment. Therefore, early detection and early treatment become the best way to reduce the mortality of ovarian cancer. The 5-year survival rate of ovarian cancer detected early is up to 95%. It has been the focus of clinical work to find tumor markers that can help diagnose ovarian cancer early.