急性重症胰腺炎(severe acute pancreatitis,SAP)是临床上常见的急危重症疾病,SAP的发生和发展是多因素、多环节共同作用的结果。近年来,虽然对SAP的治疗取得了一定进展,随着对急性胰腺炎病理生理认识的深入,炎症细胞因子在急性胰腺炎中的作用逐渐受到人们的关注,研究表明,SAP早期病情变化与细胞因子的过度释放有着密切关系~([1])。通过探讨腹膜透析与血液滤过在SAP治疗中清除炎性介质的有效 Severe acute pancreatitis (SAP) is a common and critically ill disease in clinic. The occurrence and development of SAP are the result of multi-factor and multi-link co-operation. In recent years, although the treatment of SAP has made some progress, with the deepening understanding of the pathophysiology of acute pancreatitis, the role of inflammatory cytokines in acute pancreatitis has gradually attracted the attention of people, studies have shown that SAP early changes in disease and cells The excessive release of factors is closely related to ~ ([1]). By exploring peritoneal dialysis and hemofiltration in the treatment of SAP in the removal of inflammatory mediators effective