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本文对35例在睡眠中发作的儿童癫痫(观察组)与同期非睡眠中发作的38例儿童癫痫(对照组)进行随访、对比分析。发现前者在临床上虽以全身性发作为主(65.7%),但EEG多呈局限性异常(62.9%),大多数(97.1%)于睡后或醒前2小时内发作。观察组与对照组癫痫发作缓解2年以上者分别占80%和44.7%,其中经药物治疗缓解2年以上者分别为73.3%和40%,5年以上长期缓解率分别为26.7%、5.7%。智力发育迟缓者分别为3.7%和21.4%。本文结果表明,观察组发作缓解率或治愈率均明显优于对照组,且对儿童智力发育无明显影响。
Thirty-five children with epilepsy (observation group) attacked during sleep episode and 38 children with epilepsy (control group) attack during non-sleep over the same period were followed up and compared. Although the former is mainly characterized by a systemic attack (65.7%), EEG showed mostly localized abnormalities (62.9%), with the majority (97.1%) attacking within two hours after sleep or before waking. The observation group and the control group were 80% and 44.7%, respectively, whose remission for more than 2 years was seizure. The long-term remission rates were 73.3% and 40% respectively after more than 2 years of drug treatment. The long-term remission rates after 5 years were 26.7% and 5.7% . Mental retardation were 3.7% and 21.4% respectively. The results show that the observation group seizure remission rate or cure rate were significantly better than the control group, and no significant impact on children’s intellectual development.