吴某,男,46岁,本人表型与智力正常,生三女均智力低下而作染色体核型分析。吴某为 46,xy,inv(9)(p~(13);q~(13)),其长女19岁、次女16岁、三女12岁染色体核型均为46,xx,inv(9)(p~(13);q~(13)),其妻表型及智力正常,其父母为姑舅结婚,吴某父亲染色体核型46,xy 正常。国外报道在新生儿调查中9号染色体臂间倒位发生率为0.95～1.2%。李麓云 Wu, male, 46 years old, my phenotype and mental normal, three girls have mental retardation and chromosomal karyotype analysis. Wu was 46, xy, inv (9) (p ~ (13); q ~ (13)). The eldest daughter was 19 years old and the second daughter was 16 years old. 9) (p ~ (13); q ~ (13)), his wife phenotype and intelligence normal, his parents married uncle, Wu father chromosome karyotype 46, xy normal. Foreign reports in the newborn survey 9 chromosome inversion occurred between the rate of 0.95 to 1.2%. Li Lu Yun