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目前认为生长激素(GH)缺乏是原发性骨质疏松发病的一个重要因素。为了证实这一作用,作者通过测定原发性骨质疏松、退行性骨病和正常对照者血类胰岛素生长因子1和2(IGFs)及其主要结合蛋白3(BP-3)作为间接指标,观察GH的内源性分泌水平。对象和方法共310例,其中原发性骨质疏松和椎骨骨折病人(OPO)141例(男43例、女98例),脊椎退行性骨病和骨关节炎病人(DEG)108例(男17、女91),正常对照(仅有轻度腰脊痛、X-线
Now that the lack of growth hormone (GH) is an important factor in the incidence of primary osteoporosis. To confirm this effect, the authors measured blood levels of insulin-like growth factor 1 and 2 (IGFs) and its major binding protein 3 (BP-3) as primary markers of primary osteoporosis, degenerative bone disease, Observe the endogenous secretion of GH. Subjects and methods A total of 310 cases, including primary osteoporosis and vertebral fracture patients (OPO) 141 cases (43 males and 98 females), spinal degenerative osteoarthritis and osteoarthritis patients (DEG) 108 cases (male 17, female 91), normal control (only mild lumbar pain, X-ray