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本文用双波长分光度法对益康唑的一些制剂中益康唑的含量测定,可不经分离直接测定,另根据文献报道,测定益康唑含量是采用酸性甲醇溶液作为测定稀释剂,考虑甲醇具有毒性大,挥发性也大,价钱贵,故本测定方法改用乙醇作为测定溶剂,经试验结果表明,与酸性甲醇测定结果相符,因此,本法具有简单、快速、准确、安全等优点,测定结果符合要求。
In this paper, two-wavelength spectrophotometric determination of econazole in some formulations of econazole content can be directly measured without isolation, according to the other reported in the literature, the determination of econazole content is the use of acidic methanol solution as a measuring diluent, taking into account the methanol The method has the advantages of high toxicity, large volatility and high price. Therefore, the method of the present invention uses ethanol as the measuring solvent, and the test result shows that the method is in good agreement with the acid methanol determination result. Therefore, the method has the advantages of simple, rapid, accurate and safe, Determination of the results to meet the requirements.