论文部分内容阅读
目的探讨甲状腺功能亢进性心脏病的超声心动图表现及相关危险因素。方法回顾分析361例甲亢患者(包括单纯甲亢及甲亢性心脏病患者)的超声心动图资料、一般临床资料及检测指标。结果单纯甲亢患者的左心室射血分数(LVEF)高于甲亢性心脏病(P<0.01),两组间左心房、左心室大小差异有统计学意义(P<0.05)。甲亢性心脏病组患者年龄、病程(P<0.01)、血清游离甲状腺素(FT4)水平、甲状腺体积及重量、收缩压和脉压差(P<0.05)均显著高于单纯甲亢组,血浆总胆固醇和三酰甘油均低于甲亢组(P<0.05)。结论年龄、病程及FT4水平是甲亢性心脏病的主要危险因素,超声心动图检查有助早期发现甲亢患者心脏结构和功能改变。
Objective To investigate the echocardiographic manifestations and related risk factors of hyperthyroid heart disease. Methods The echocardiographic data, general clinical data and testing indexes of 361 hyperthyroid patients (including simple hyperthyroidism and hyperthyroid heart disease) were retrospectively analyzed. Results Left ventricular ejection fraction (LVEF) was significantly higher in patients with hyperthyroidism than those with hyperthyroidism (P <0.01). There was significant difference in the size of left atrium and left ventricle between two groups (P <0.05). Hyperthyroidism group patients age, duration (P <0.01), serum free thyroxine (FT4) level, thyroid volume and weight, systolic blood pressure and pulse pressure difference were significantly higher than those in hyperthyroidism group alone Cholesterol and triglyceride were lower than hyperthyroidism group (P <0.05). Conclusions Age, course of disease and FT4 level are the main risk factors of hyperthyroidism heart disease. Echocardiography can help early detect the changes of cardiac structure and function in patients with hyperthyroidism.