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目的:探讨中药软坚止痛膏外用治疗癌症疼痛的临床疗效并分析其意义。方法:将103例患者随机分为治疗组51例和对照组52例,对照组按照癌痛三阶梯给药原则予西药常规治疗,治疗组在此基础上,加用软坚止痛膏,每次6~8h,每天2次。观察两组患者疼痛缓解程度、临床疗效、视觉模拟评分(VAS)以及KPS评分等。结果:治疗2个疗程后,两组癌痛缓解总有效率比较差异有统计学意义(P<0.05),两组VAS评分较治疗前均有明显下降(P<0.05),两组KPS评分比较差异具有统计学意义(P<0.05)。在中度疼痛患者中,治疗组的疗效优于对照组,两组比较差异有统计学意义(P<0.05)。结论:中药软坚止痛膏配合阶梯口服药与单纯三阶梯口服药相比,具有协同作用,在镇痛方面具有明显疗效,提高了患者的生活质量,尤其对中度疼痛的疗效高于重度疼痛的疗效。
Objective: To explore the clinical efficacy of Chinese herbal medicine Ruanjian Zhitong cream in the treatment of cancer pain and analyze its significance. METHODS: 103 patients were randomly divided into treatment group (51 cases) and control group (52 cases). The control group was given western medicine routine treatment according to the principles of cancer pain three ladders, and the treatment group was given the addition of soft firming pain relief cream, each time 6 ~8h, 2 times a day. The degree of pain relief, clinical efficacy, visual analogue scale (VAS), and KPS scores were observed in both groups. Results: After two courses of treatment, the total effective rate of cancer pain relief in the two groups was statistically significant (P<0.05). The VAS scores of both groups were significantly lower than before treatment (P<0.05). The KPS scores of the two groups were compared. The difference was statistically significant (P<0.05). In moderate pain patients, the curative effect of the treatment group was better than that of the control group, and the difference between the two groups was statistically significant (P<0.05). Conclusion: The combination of traditional Chinese medicine Ruanjian Zhitong ointment and stepped oral medicine has a synergistic effect compared with simple three-step oral medication. It has obvious curative effect on analgesia and improves the patient’s quality of life, especially for moderate pain than severe pain. Efficacy.