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目的：了解云南拉祜族６ 个短串联重复序列基因座遗传多态性分布。方法：应用复合扩增技术对ＣＳＦ１ＰＯ、ＴＰＯＸ、ＴＨ０１ 、Ｆ１３Ａ０１、ＦＥＳＦＰＳ和ｖＷＡ等６ 个ＳＴＲ基因座进行分析，采用高分辨率的聚丙烯酰胺凝胶电泳分离、银染法显影技术，对云南拉祜族上述６ 个ＳＴＲ基因座进行遗传多态性调查。结果：ＣＳＦ１ＰＯ基因座，观察到８ 个等位基因，２０ 个基因型；ＴＰＯＸ 基因座，观察到５ 个等位基因，１４ 个基因型；ＴＨ０１ 基因座，观察到６ 个等位基因，１７ 个基因型；Ｆ１３Ａ０１ 基因座，观察到６ 个等位基因，１３ 个基因型；ＦＥＳＦＰＳ基因座，观察到７ 个等位基因，１５ 个基因型；ｖＷＡ基因座，观察到７ 个等位基因，１７ 个基因型。结论：上述６ 个短串联重复序列基因座基因频率分布与ＨａｒｄｙＷｅｉｎｂｅｒｇ 平衡吻合良好。
Objective: To understand the genetic polymorphism distribution of six short tandem repeat loci in Yunnan Lahu nationality. METHODS: Six STR loci such as CSF1PO, TPOX, TH01, F13A01, FESFPS and vWA were analyzed by multiplex amplification. High-resolution polyacrylamide gel electrophoresis and silver-staining were used to analyze the genetic diversity of pull pull Family of six STR loci genetic polymorphism survey. Results: There were 8 alleles and 20 genotypes in the CSF1PO locus. TPOX locus, 5 alleles and 14 genotypes were observed. TH01 locus, 6 alleles were observed, 17 Genotype; F13A01 locus, 6 alleles and 13 genotypes were observed; FESFPS loci, 7 alleles and 15 genotypes were observed; vWA loci, 7 alleles, 17 Genotypes. Conclusion: The frequency distribution of the six short tandem repeat loci was in good agreement with Hardy-Weinberg equilibrium.