论文部分内容阅读
目的 :探讨类风湿性关节炎 (RA)与性激素之间的关系。方法 :用放射免疫法检测了 34例男性及女性绝经期后RA患者血清性激素水平。结果 :RA患者血清睾酮 (Te)浓度明显低于正常对照组 (P <0 .0 1) ,孕酮(PRO)浓度亦低于正常对照组 (P <0 .0 5 ) ,男性RA患者血清雌二醇 (E2 )及泌乳素 (PRL)浓度均高于正常对照组 (P <0 .0 5 ) ,女性RA患者血清E2 浓度亦明显高于正常对照组 (P <0 .0 1) ,而RA患者促卵泡素 (FSH)、促黄体素 (LH)浓度及女性RA患者血清PRL浓度与正常对照组之间均无显著性差异 (P >0 .0 5 )。结论 :性激素对RA的发病有一定的影响。
Objective: To investigate the relationship between rheumatoid arthritis (RA) and sex hormones. Methods: Radioimmunoassay was used to detect the levels of serum sex hormones in RA patients after menopause and in 34 males and females. Results: Serum testosterone (Te) concentrations in patients with RA were significantly lower than those in normal controls (P <0.01) and progesterone (PRO) concentrations in patients with RA were significantly lower than those in healthy controls (P <0.05) The estradiol (E2) and prolactin (PRL) concentrations were higher than those in the normal control group (P <0.05), and the serum E2 levels in the women with RA were significantly higher than those in the normal control group (P <0.01) However, there was no significant difference between FSH, LH and serum PRL levels in women with RA (P> 0.05). Conclusion: Sex hormones have a certain impact on the incidence of RA.