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目的:比较丁卡因胶浆单用与坦索罗辛不同剂量联用治疗早泄的疗效。方法:将126例确诊为早泄的患者随机分成三组,A组使用丁卡因胶浆外用,B组使用丁卡因胶浆同时每次性生活前4~6小时服用盐酸坦索罗辛0.2mg,C组使用丁卡因胶浆同时每晚服用盐酸坦索罗辛0.2mg。观察三组患者治疗前及治疗8周及停药4周后的平均阴道内射精潜伏期(IELT)评分、性交满意度评分等。结果:三组患者IELT评分、性交满意度评分治疗前与治疗8周后比较,差异均有统计学意义(P<0.01);而治疗8周后三组间两两比较,差异均有统计学意义(P<0.01),停药4周后两评分明显下降,接近治疗前水平。结论:丁卡因胶浆与坦索罗辛联用可以提高早泄的疗效,且可按需使用。
Objective: To compare the curative effect of tetracaine glue alone and tamsulosin with different dosages in treating premature ejaculation. Methods: A total of 126 patients diagnosed as premature ejaculation were randomly divided into three groups. Group A was treated with tetracaine glue. Group B was treated with tetracaine glue and tamsulosin hydrochloride 0.2 at 4 to 6 hours before each sex life mg, while in group C, tetracaine gum was used and 0.2 mg tamsulosin hydrochloride was taken every night. The mean intravaginal ejaculation latency (IELT) score, sexual satisfaction score and so on were observed before treatment, 8 weeks after treatment and 4 weeks after treatment. Results: The scores of IELT and sexual intercourse satisfaction of the three groups before and 8 weeks after treatment were significantly different (P <0.01). However, the difference between the three groups was statistically significant Significance (P <0.01), after 4 weeks withdrawal two score decreased significantly, close to the level before treatment. Conclusion: Tetracaine glue and tamsulosin can improve the efficacy of premature ejaculation, and can be used on demand.