静脉滴注奎宁对多数恶性疟疾患者(甚至合并有昏迷、黄疸或肾功能衰竭者),是有效的治疗方法。约2%的恶性疟疾患者发生像昏迷、抽搐或精神错乱等脑部症状。轻度昏迷者可在静滴小剂量奎宁或氯喹后得到改善,而深度昏迷患者尽管进行治疗亦可发生死亡。脑型疟疾的病死率仍保持在20%左右。中等程度的昏迷可持续10天左右,只有给予悉心的按量滴注奎宁、维持液体平衡和兼顾其他因素方可治愈。许多附加的治疗措施,曾试用于治疗恶性疟疾昏 Intravenous quinine is an effective treatment for most patients with malaria (even with coma, jaundice, or renal failure). About 2% of patients with malignant malaria develop brain symptoms such as coma, convulsions or insanity. Mild coma can be improved by intravenous infusion of low doses of quinine or chloroquine, while death can occur in patients with deep coma despite treatment. The mortality rate of cerebral malaria remains around 20%. Moderate coma can last about 10 days, only given a careful infusion of quinine by volume, to maintain liquid balance and take into account other factors before cure. Many additional treatments have been tried to treat falciparum malaria