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目的观察那格列奈与肾炎康复片联合治疗糖尿病肾病的效果。方法 320例糖尿病合并糖尿病肾病患者,分为两组:对照组160例给予那格列奈与金水宝胶囊,观察组160例给予那格列奈与肾炎康复片联合治疗,均治疗12周,观察治疗前后,空腹血糖(FBG),餐后2h血糖(2hPBG),糖化血红蛋白(HbA1c),24h尿微量白蛋白定量UAE及肾功能的变化,进行对比研究。结果观察组患者在24h尿微量白蛋白的定量,肾功能的变化方面明显优于对照组。结论 2型糖尿病患者合并糖尿病肾病使用那格列奈联合肾炎康复片治疗,效果明显,肾功能及24h尿微量白蛋白的定量明显下降,值得推广。
Objective To observe the effect of nateglinide and nephritis kang tablet in the treatment of diabetic nephropathy. Methods A total of 320 diabetic patients with diabetic nephropathy were divided into two groups: control group (n = 160), nateglinide and Jinshuibao capsule (n = 160) and nateglinide combined with nephritis (n = 12) Fasting blood glucose (FBG), postprandial 2h blood glucose (2hPBG), glycosylated hemoglobin (HbA1c), 24h urine microalbuminuria UAE and renal function changes before and after treatment were compared. Results The observation group patients in 24h urinary albumin quantitative, renal function was significantly better than the control group. Conclusion Patients with type 2 diabetes mellitus and diabetic nephropathy treated with nateglinide combined with nephritis and konjac are effective in reducing the renal function and urinary microalbuminuria in 24h, which deserves promotion.