论文部分内容阅读
本文报道用附子Ⅰ号注射液静脉滴注治疗因冠心病、心肌炎后遗症等引起的缓慢型心律失常(房室传导阻滞、病态窦房结综合征)14例;其显效率为23.0％,总有效率达77.0％。本药能促进改善窦房结、房室结节律及传导功能,能快速提高心率及改善房室传导阻滞病变,但作用持续时间短暂。对血压影响一般升降在10～20毫米汞柱。有一过性的副反应。在动物实验中,用药后,希氏束电图上表现A-H间期明显缩短,H波、H-V间期改变不明显,这阐明了临床上改善房室传导阻滞病变的机理;对血压的影响:升高收缩压,降低舒张压;心率增快明显;类似异丙基肾上腺素作用,其结果与临床观察一致。
In this paper, 14 cases of slow arrhythmia (atrioventricular block, sick sinus syndrome) caused by coronary heart disease and myocarditis sequelae were treated with the injection of aconite Ⅰ by intravenous injection. The effective rate was 23.0% Effective rate of 77.0%. The drug can promote the improvement of the sinus node, atrioventricular node rhythm and conduction, can quickly improve heart rate and improve atrioventricular block disease, but the duration of action is short. The general impact on blood pressure movements in 10 ~ 20 mm Hg. Have a transient side effects. In animal experiments, after treatment, the His group showed a marked shortening of the AH interval on the BEF, H wave, HV interval was not obvious, which illustrates the clinical mechanism of atrioventricular block to improve the impact of blood pressure : Increased systolic blood pressure, decreased diastolic blood pressure; heart rate increased significantly; similar to isoproterenol, the results consistent with clinical observations.