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目的 :评价后程超分割放射治疗脑肿瘤的疗效。方法 :对 30例脑肿瘤术后患者进行后程超分割放射治疗 (常规放疗至DT30～ 4 0Gy后 ,按 1 2Gy/次 ,2次 /天 ,间隔 6小时以上进行照射 ,总剂量 6 0Gy) ,与同期 30例采用常规分割放射治疗的脑肿瘤病人作为对照组 (照射方法为 2 0 0cGy/次 ,1次 /天 ,总剂量 5 0～ 5 6Gy/ 2 5～ 30次 / 5～ 6周 )进行 1、3、5年生存率的比较。结果 :后程超分割组与常规分割组的 1、3、5年生存率分别为 6 3%、31%、11%和 5 3%、4 0 3%、2 0 % ,2组无显著性差异(P >0 0 5 )。结论 :后程超分割放射治疗脑肿瘤较常规分割放射治疗不能明显提高生存率
PURPOSE: To evaluate the efficacy of late-stage hyperfractionated radiation in the treatment of brain tumors. Methods: Thirty patients with post-operative brain tumor underwent late-course hyperfractionated radiotherapy (conventional radiotherapy to DT30 ~ 40 Gy followed by 1 2Gy / time, 2 times / day, with an interval of more than 6 hours for a total dose of 60 Gy) , And compared with 30 cases of brain tumor patients underwent conventional fractionated radiotherapy at the same period as the control group (irradiation method: 200 cGy / time, once daily, total dose: 50 ~ 56 Gy / 25 ~ 30 times / 5-6 weeks ) 1, 3, 5 year survival rate comparison. Results The 1, 3, 5-year survival rates of the latter group were 63%, 31%, 11% and 53%, 40% and 20% respectively, but there was no significant difference between the two groups Difference (P> 0.05). Conclusions: Late-stage hyperfractionated radiotherapy of brain tumors does not significantly improve survival compared with conventional fractionated radiotherapy