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目的 探讨妊高征患者血浆可溶性P -选择素 (SP -选择素 )检测的意义。方法 用ELISA方法检测 4 9例妊高征患者 (研究组 )及 2 0例正常妊娠妇女 (对照组 )血浆SP -选择素的含量。结果 血浆SP -选择素在妊高征组明显高于正常妊娠组 (P <0 0 0 1) ,增高程度与妊高征病情严重程度呈正相关。结论 血浆SP -选择素与妊高征病程发展有关 ;监测妊高征患者血浆SP -选择素水平有助于妊高征病情分析
Objective To investigate the significance of plasma soluble P - selectin (SP - selectin) in patients with pregnancy induced hypertension. Methods The levels of plasma SP - selectin in 49 cases of PIH (study group) and 20 normal pregnant women (control group) were detected by ELISA. Results Plasma SP - selectin was significantly higher in the PIH group than in the normal pregnancy group (P <0.01). The level of plasma SP - selectin was positively correlated with the severity of PIH. Conclusions Plasma SP - selectin is associated with the progression of PIH. Monitoring plasma SP - selectin level in patients with PIH is helpful for the analysis of the condition of PIH