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目的 观察国产rhGM CSF对 5 5例肿瘤患者化疗所致WBE和ANE减少的防治作用及副反应。方法 采用多中心、单盲配对、自身交叉对照的方法。结果 rhGM CSF对肿瘤化疗所致的骨髓抑制、白细胞及粒细胞降低均有治疗及预防作用 ,副反应轻微 ,患者均可耐受。结论 rhGM CSF是肿瘤患者化疗后的一种有价值的辅助治疗药物
Objective To observe the prevention and treatment effect of domestic rhGM CSF on the reduction of WBE and ANE induced by chemotherapy in 55 patients with tumor and its side effects. Methods Multi-center, single-blind pairing, self-cross-control method. Results rhGM CSF had therapeutic and preventive effects on myelosuppression, leukopenia and neutropenia induced by chemotherapy. The side effects were mild and patients were tolerant. Conclusion rhGM CSF is a valuable adjuvant therapy for cancer patients after chemotherapy