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12例麻醉狗结扎左冠状动脉前降支(LAD)后心室内压最大下降速率(peak negative dp/dt,简称-dp/dt_(max))的变化显著早于最大上升速率(dp/dt_(mlx))、ST段和其它血流动力学指标的改变。阻断LAD后左室内压下降时间常数较对照值延长3.9±1.0ms(p<0.005),其延长的例数占83.3%。
The changes of peak negative dp / dt (dp / dt max) in 12 anesthetized dogs after LAD occlusion were significantly earlier than those of maximal rate of increase (dp / dt_ ( mlx)), changes in ST-segment and other hemodynamic parameters. The time constant of left ventricular pressure drop after blocking LAD was prolonged by 3.9 ± 1.0 ms (p <0.005) compared with the control value, and the prolonged number of cases was 83.3%.