肝微粒体混合功能氧化酶是一些膜结合酶,它直接参与体内的许多重要代谢过程,例如各种外来化合物如农药、致癌物、药物和一些内源性物质如类固醇、脂肪酸,胆汁酸在机体内的代谢过程,都与微粒体混合功能氧化酶有关。大量实验证明,很多外来化合物也可影响哺乳动物肝微粒体混合功能氧化酶的活力,具体表现为诱导或抑制。肝微粒体混合功能氧化酶活力的改变,又可影响外来化合物在体内代谢的性质和速度,以致使外来 Liver microsomal mixed-function oxidases are membrane-bound enzymes that directly participate in many important metabolic processes in the body, such as various foreign compounds such as pesticides, carcinogens, drugs and some endogenous substances such as steroids, fatty acids, and bile acids in the body Metabolic processes within the microsome are associated with functional oxidases. Numerous experiments have shown that many extraneous compounds can also affect the activity of mammalian liver microsomal mixed-function oxidase, manifested as induction or inhibition. Liver microsomal mixed-function oxidase activity changes, but also affect the nature and speed of foreign compounds in the body metabolism, so that foreign