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目的为探讨肺表面活性物质联合经鼻气道正压通气对极低出生体重儿NRDS的预防价值。方法将2005年1月至2008年12月期间收住我科的极低出生体重儿73例按是否早期使用PS分为预防组(30例)及对照组(40例),比较其NRDS的发病率及存活率。结果预防组的NRDS及并发症的发生率较对照组明显降低(P<0.05)。结论早期使用PS并联合经鼻气道正压通气可有效预防极低出生体重儿的NRDS的发病率,并改善NRDS的治疗效果。
Objective To investigate the preventive effect of pulmonary surfactant combined with nasal positive airway pressure on the NRDS of very low birth weight infants. Methods 73 cases of very low birth weight infants admitted to our department from January 2005 to December 2008 were divided into prevention group (30 cases) and control group (40 cases) according to whether they were used early or late. The incidence of NRDS was compared Rate and survival rate. Results The incidence of NRDS and complications in the prevention group was significantly lower than that in the control group (P <0.05). Conclusions The early use of PS combined with transnasal positive airway pressure can effectively prevent the incidence of NRDS in very low birth weight infants and improve the therapeutic effect of NRDS.