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目的:总结中西医结合治疗早中期慢性肾功能不全的疗效,为临床提供重要依据。方法:将108例患者随机分为对照组和治疗组。对照组52例患者均给予低磷饮食及优质低蛋白,其中,蛋白质的摄入量必须小于或者等于0.6g/kg·d,服用保肾康片,每天服用3次,每次4片,同时选择一定量的肾必氨基酸进行静脉滴注,剂量通常选择250ml。每天静脉滴注肾必氨基酸1次,一个疗程为3个月,需治疗一个疗程。治疗组56例患者均实施与对照组一样的治疗,同时在对照组的基础上加用中药补脾化浊汤。补脾化浊汤主要为水煎,每天需服用1剂,一般为400ml,在早晨和晚上两个阶段分别分别服用。56例患者皆依据具体病情实施必要的纠正水电解质紊乱、抗感染、降压、改善代谢性酸中毒等治疗。结果:治疗组总有效率为78.6%。对照组总有效率为61.5%。两组治疗效果相比,治疗组总有效率明显高于对照组,存在统计学意义(P<0.05)。结论:对于早中期的慢性肾功能不全患者,实施中西医结合治疗,可取得满意的疗效,值得在临床实践中推广使用。
OBJECTIVE: To summarize the curative effect of integrative traditional Chinese and western medicine on early and mid-term chronic renal insufficiency and provide an important basis for clinical practice. Methods: 108 patients were randomly divided into control group and treatment group. The control group of 52 patients were given a low-phosphorus diet and high-quality low-protein, of which the protein intake must be less than or equal to 0.6g / kg · d, taking Baoshenkang tablets, taking 3 times a day, each 4 tablets, at the same time Select a certain amount of renal essential amino acids for intravenous infusion, the dose is usually selected 250ml. Daily intravenous administration of renal essential amino acids 1, a course of treatment for 3 months, need to treat a course of treatment. 56 patients in the treatment group were treated with the same treatment as the control group, while the traditional Chinese medicine Bupi Huazhuo Decoction was added on the basis of the control group. Spleen Huazhuo Decoction mainly for decoction, take 1 dose daily, usually 400ml, were taken in the morning and evening, respectively, two stages. 56 patients were based on the specific conditions necessary to correct the water and electrolyte disorders, anti-infective, antihypertensive, metabolic acidosis and other treatment. Results: The total effective rate was 78.6% in the treatment group. The control group, the total effective rate was 61.5%. The total effective rate of the treatment group was significantly higher than that of the control group, there was statistical significance (P <0.05). Conclusion: For patients with chronic renal insufficiency in the early and middle stages, the implementation of Integrative Medicine can achieve satisfactory results and is worth promoting in clinical practice.