子宫动脉栓塞术治疗子宫肌瘤的研究进展

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子宫肌瘤又称子宫平滑肌瘤,是女性生殖器官中最常见的良性肿瘤,育龄妇女发病率达到了20-25%,尽管多数患者无症状,但仍有10-40%的子宫肌瘤妇女需要治疗,常见的症状是月经过多、过频及经期延长,盆腔疼痛及邻近器官的压迫症状如尿频、排便困难,继发性贫血,不孕等,严重影响了患者的身体健康。子宫肌瘤的传统治疗方法是以手术为主辅以药物治疗。子宫切除术不易被未生育或较年轻的妇女所接受,而肌瘤剔除术复发率高达20%~25%;药物治疗子宫肌瘤的疗效不理想且副作用多。故对有症状性子宫肌瘤,经保守治疗失败又需保留生育能力或较年轻的患者的处理,是妇科医生面临的难题。近十年来,国内外学者采用子宫动脉栓塞术(uterine arterial embolization,UAE)治疗子宫肌瘤引起的月经过多、贫血和缩小瘤体,疗效显著,为子宫肌瘤患者的治疗提供了一个有效的手段。其治疗机制是通过阻断肿瘤的供血动脉,达到肌瘤去血管化,导致肌瘤缺血缺氧、变性、坏死、吸收,从而达到治疗的目的。临床总结UAE治疗子宫肌瘤有效率90%以上,是一项全新、微创、有效的治疗方法。 Uterine fibroids, also known as uterine leiomyoma, is the most common benign tumor in female genital mutilation, the incidence of women of childbearing age reached 20-25%, although most patients are asymptomatic, but there are still 10-40% of women with uterine fibroids Need to be treated, common symptoms are menorrhagia, excessive frequency and menstrual prolongation, pelvic pain and oppression of adjacent organs such as urinary frequency, defecation difficulties, secondary anemia, infertility, etc., seriously affecting the patient’s health. The traditional treatment of uterine fibroids is mainly based on surgery with drug treatment. Hysterectomy is not easily accepted by women who are not fertile or young, and myoma excision recurrence rate as high as 20% to 25%; drug treatment of uterine fibroids less than ideal and side effects. Therefore, the treatment of symptomatic uterine fibroids, conservative treatment failed to retain fertility or younger patients handling, gynecologists are facing problems. In the past decade, uterine arterial embolization (UAE) has been used by domestic and foreign scholars for the treatment of uterine fibroids caused by menorrhagia, anemia and tumor shrinkage, with significant curative effect, which has provided an effective means. The treatment mechanism is by blocking the blood supply artery of the tumor to fibrovascular degranulation, resulting in myogenic hypoxia ischemia, degeneration, necrosis, absorption, so as to achieve the purpose of treatment. Clinical summary UAE treatment of uterine fibroids more than 90% efficiency, is a new, minimally invasive, effective treatment.
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