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目的探讨通乳颗粒对产后催乳的疗效及安全性,为促进母乳喂养提供科学依据。方法选取2014年8月-2015年3月在该院生产的孕产妇为研究对象,根据患者的意愿分成试验组和对照组。对照组给予产科常规护理措施,采用产后综合康复治疗仪进行乳房按摩,不给予任何其他促进乳汁分泌的治疗手段;试验组在对照组的基础上给予通乳颗粒口服。对两组研究对象的哺乳满足率、人工喂养次数、母体血清泌乳素水平、新生儿经皮胆红素水平、乳汁中slg A含量、乳房胀痛情况、新生儿不良事件发生情况、产妇生命体征、子宫复旧和恶露情况、产妇的血尿常规、肝肾功能等实验室检查情况、心电图检查、产后30 d新生儿发育情况进行分析。结果试验组研究对象服药后第2、3、4天及停药第1天的哺乳满足率、血清泌乳素水平显著高于对照组,人工喂养次数、新生儿经皮胆红素水平显著低于对照组,差异有统计学意义(P<0.05);而服药后第1天与对照组的差异无统计学意义(P>0.05);停药第1天的血清泌乳素水平较对照组高,乳房胀痛程度较对照组轻,差异均有统计学意义(P<0.05),而两组研究对象乳汁中s Ig A的含量则基本一致,差异无统计学意义(P>0.05)。试验组产妇在停药第1天的宫底位置较对照组低,红色恶露比例较对照组低,差异有统计学意义(P<0.05)。结论将通乳颗粒应用于产后催乳安全有效,值得在临床上推广应用。
Objective To investigate the efficacy and safety of Tongru granule on postpartum lactation and provide a scientific basis for promoting breastfeeding. Methods The pregnant women who were hospitalized in this hospital from August 2014 to March 2015 were selected as study subjects and divided into experimental group and control group according to their wishes. The control group was given general obstetric nursing measures, postpartum comprehensive rehabilitation instrument for breast massage, do not give any other means to promote the secretion of milk; experimental group in the control group given Tongru granule oral. Satisfaction rate of breastfeeding, number of artificial feeding, maternal serum prolactin level, neonatal transcutaneous bilirubin level, breast milk slg A content, breast tenderness, neonatal adverse events, maternal vital signs , Uterine involution and lochia situation, maternal blood and urine routine, liver and kidney function laboratory tests, electrocardiogram, postpartum 30 d neonatal development were analyzed. Results The lactation satisfaction rate and serum prolactin level of the experimental group on the 2nd, 3rd, 4th day and the 1st day of withdrawal were significantly higher than those of the control group. The times of artificial feeding and neonatal transcutaneous bilirubin were significantly lower than those of the control group (P <0.05). There was no significant difference between the control group and the first day after administration (P> 0.05). The level of serum prolactin on the first day of withdrawal was higher than that of the control group The degree of breast pain was lighter than that of the control group (P <0.05), while the content of s Ig A in milk of the two groups was basically the same, with no significant difference (P> 0.05). In the experimental group, the position of the uterus at the first day of withdrawal was lower than that of the control group, and the proportion of red lochia was lower than that of the control group (P <0.05). Conclusion The application of Tongru granule in postpartum lactation is safe and effective, which is worth popularizing in clinic.