The role of the HGF/c-Met signaling pathway in crizotinib-induced apoptosis in lung cancer with c-Me

来源 :肿瘤学与转化医学：英文版 | 被引量 : 0次 | 上传用户：yt66896915

【摘要】

：

Objective This study aimed to study the role of the HGF/c-Met signaling pathway in crizotinib-induced apoptosis of various lung adenocarcinoma cell lines and xe

【作者】

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Shaozhang Zhou Zhixin Dong Jin

【机构】

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TheSecondDepartmentofChemotherapy,GuangxiMedicalUniversityGraduateSchool

【出处】

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肿瘤学与转化医学：英文版

【发表日期】

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2017年3期

【关键词】

：

细胞凋亡信号通路丝氨酸/苏氨酸蛋白激酶基因扩增诱导 Apoptosis A549细胞异种移植 HGF/c-MET signaling pathway

【基金项目】

：

Supported by grants from the National Natural Sciences Foundation of China（No.81060188 and No.81260351）, Guangxi Sciense＆Technology Development Funds（No.2015139 and No.201017）

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Objective This study aimed to study the role of the HGF/c-Met signaling pathway in crizotinib-induced apoptosis of various lung adenocarcinoma cell lines and xenograft tumor models.Methods In vitro, H2228, H1993, and A549 cells were treated with crizotini

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The role of the HGF/c-Met signaling pathway in crizotinib-induced apoptosis in lung cancer with c-Me

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