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目的 分析广东省 2 0 0 3年严重急性呼吸综合征 (severeacuterespiratorysyndrome,SARS)流行特征 ,探讨其危险因素 ,为有效控制该病的流行提供对策、依据与参考。方法 用描述流行病学方法对SARS流行病学及控制措施等相关资料进行描述与分析。结果 目前追溯到首例发病日期为 2 0 0 2年 11月 16日 ,家庭聚集发病 5例 ;2 0 0 3年 1月 2日 ,河源市为全国最早正式报告SARS病例的城市。至 2 0 0 3年 6月 15日止 ,广东省共有 15个地级市报告SARS病例 15 11例 ,全省报告发病率为 1 77/10万 ,主要集中在珠江三角洲的 5个城市 (佛山、广州、深圳、中山及江门 ) ,占病例总数的 95 97% ,广州市报告病例最多 ,占病例总数的 85 81% ;报告死亡数为 5 8例 ,报告死亡率为 0 0 7/10万 ,病死率为 3 84 %。发病高峰出现在 1月 2 8日至 2月 2 6日 (占病例总数的 5 0 6 9% ) ,单日发病例数最多的为 2月 8日 ,共 5 5例。发病年龄主要集中在青壮年 (2 0～ 4 9岁 ) ,占 6 5 86 %。发病率随着年龄的增大而升高。有明显的医院和家庭聚集现象 ,医务人员的聚集性病例占病例总数的19 38% ,家庭聚集性病例占 12 0 4 %。早期 135例无明确接触史的社区散发患者中 ,从事与动物相关职业者 11例 ,占 8 14 %。潜伏期为 1～ 12d ,中位
Objective To analyze the epidemiological characteristics of severe acute respiratory syndrome (SARS) in Guangdong Province in 2003 and to explore its risk factors so as to provide countermeasures, basis and reference for effectively controlling the epidemic of the disease. Methods Descriptive epidemiological methods were used to describe and analyze SARS epidemiology and control measures. The results date back to the first case of onset date of November 16, 2002, the incidence of family aggregation in 5 cases; January 2, 2003, Heyuan City, the earliest official reporting of SARS cases in cities. As of June 15, 2003, a total of 15 11 SARS cases were reported in 15 prefecture-level cities in Guangdong Province. The province’s reported incidence was 1 77/10 million, mainly in five cities in the Pearl River Delta (Foshan Guangzhou, Shenzhen, Zhongshan and Jiangmen) accounted for 95.97% of the total number of cases. Guangzhou reported the largest number of cases, accounting for 85.81% of the total number of cases. The reported deaths were 58 cases and the reported mortality rate was 0 0/7/10 million The case fatality rate was 3 84%. The peak incidence peaked from January 28 to February 26 (accounting for 5 0 6 9% of the total number of cases). The highest number of single-day cases was February 8, a total of 55 cases. Age of onset mainly concentrated in young adults (20 ~ 49 years old), accounting for 6585%. Incidence increases with age. There was a clear phenomenon of hospital and family aggregation, with 19 38% of the total number of cases of medical staff being grouped together and 124.4% of cases of family aggregation. In the early 135 cases of community-based patients without a definite history of exposure, 11 were engaged in animal-related occupations, accounting for 8 14%. The incubation period of 1 ~ 12d, the median