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目的比较爱迪注射液配合化疗(治疗组)与单纯化疗(对照组)对晚期结肠癌的疗效、生活质量及免疫功能的影响。方法62例晚期结肠癌患者随机分为爱迪注射液配合化疗组(治疗组)与单纯化疗组(对照组),连续治疗4周,并比较两组间疗效、生活质量及免疫功能。结果有效率治疗组43.7%,对照组33.3%,两组比较差异无显著性(P>0.05)。治疗组生活质量评分治疗组高于对照组,两组间差异有显著性(P<0.05)。治疗组治疗前后毒性反应、免疫功能改变明显低于对照组,差异有显著性(P<0.05)。结论爱迪注射液与化疗联用治疗晚期结肠癌,可降低化疗对患者免疫功能的影响及毒副反应,改善患者的生活质量。
Objective To compare the effects of Aidi injection with chemotherapy (treatment group) and chemotherapy alone (control group) on the efficacy, quality of life and immune function of advanced colon cancer. Methods Sixty-two patients with advanced colon cancer were randomly divided into Aidi injection with chemotherapy group (chemotherapy group) and chemotherapy alone group (control group) for 4 weeks. The efficacy, quality of life and immune function were compared between the two groups. Results The effective rate was 43.7% in the treatment group and 33.3% in the control group, with no significant difference between the two groups (P> 0.05). The quality of life score of the treatment group was higher than that of the control group, the difference was significant (P <0.05). Before and after treatment, the toxicity and immune function of the treatment group were significantly lower than those of the control group (P <0.05). Conclusion Aidi injection combined with chemotherapy for advanced colon cancer can reduce the impact of chemotherapy on immune function and side effects of patients and improve the quality of life of patients.