目的:调查静安区1996~2005年围产儿死亡率,探讨围产儿死亡原因。方法:静安区1996~2005年出生的围产儿作为调查对象,计算出围产儿死亡率,进行死亡因素分析。结果:1997年死亡率达高峰,其后有显著下降趋势(P<0.05),2004年后又有所上升;畸形显著影响围产儿死亡(P<0.05)。结论:1996~2005年静安区围产儿死亡率1997年达高峰,其后逐年下降;畸形是影响围产儿死亡的最主要原因。 Objective: To investigate the perinatal mortality rate in Jingan District from 1996 to 2005 and to explore the causes of perinatal death. Methods: Perinatal children born from 1996 to 2005 in Jing’an District were investigated, and the perinatal mortality rate and death factor analysis were calculated. Results: The mortality rate peaked in 1997 with a significant downward trend thereafter (P <0.05), and then increased after 2004; deformity significantly affected perinatal mortality (P <0.05). Conclusion: The death rate of perinatal children in Jing’an District reached a peak in 1997 from 1996 to 2005, and then decreased year by year. Deformity was the most important cause of perinatal death.