论文部分内容阅读
老年人由于机体生理性老化,组织器官的细胞数目、形态及功能的变异,尤其是肝、肾功能的藏退,导致对药物的代谢、排泄能力降低,对许多药物的敏感性增高,而对药物毒副作用的对抗能力却减弱。因此,老年人用药不仅易发生药物不良反应,而且往往较青壮年人反应严重。有人调查1160例住院病人,发现70～79岁的病人中有21.3％发生药物不良反应,而20～29岁的病人中仅有3％。即使是一些较安全的常用药物对老年人有时也可发生严重的不良反应,甚至危及生命。本文就对老年人易引起不良反应的一些常用药物概述如下:
Due to the physiological aging of the body, the variation of cell number, morphology and function of tissues and organs, especially the hiding and retreat of liver and kidney functions, the metabolism and excretion ability of the drug are lowered and the sensitivity to many drugs is increased. Drug toxicity side effects of confrontational ability is weakened. Therefore, the elderly medication is not only prone to adverse drug reactions, and often more serious reactions than young people. Some 1160 inpatients were investigated and 21.3% of patients 70-79 years old were found to have adverse drug reactions compared with only 3% of those aged 20-29 years. Even some of the more commonly used safer drugs can sometimes have serious adverse effects on the elderly, even life-threatening. This article on the elderly prone to adverse reactions caused by some commonly used drugs are summarized as follows: