研究表明,食品添加剂溴酸钾对昆明种小鼠的LD50为1.58g/kg,LD50 95%可信限为1.22～2.05g/kg,属低毒。溴酸钾在昆明种小鼠体内的蓄积系数K>5.0,呈弱蓄积,且有耐受性。当剂量达到0.198g/kg时,溴酸钾能引起昆明种小鼠骨髓多染性红细胞微核形成率的增加,且存在剂量—反应关系,实验有重现性。 Studies have shown that food additives potassium bromate Kunming mice LD50 of 1.58g / kg, LD50 95% confidence limits of 1.22 ~ 2.05g / kg, is a low toxicity. Potassium bromate in Kunming mice in vivo accumulation coefficient K> 5.0, was weak accumulation, and tolerated. When the dosage of 0.198g / kg, potassium bromate can cause Kunming mice bone marrow polychromatic erythrocyte micronuclei formation rate increases, and there is a dose-response relationship, the experiment was reproducible.