甲状旁腺机能亢进症时,甲状旁腺细胞过度复制和 PTH 分泌的原因仍不太清楚。11染色体上“肿瘤控制器基因”的缺失以及单性系的证据在一些(30%)散在性的甲状旁腺腺瘤研究中得到证实;有报告在原发性家族性甲状旁腺增殖症患者发现循环的有丝分裂因子,然而大部分人体甲状旁腺腺瘤的病因仍未得到解释;同样,刺激慢性肾衰患者引起甲状旁腺细胞增殖的原因也不清楚。本文作者旨在揭示人体甲状旁腺腺瘤 PTH 分泌与甲状旁腺分泌蛋白(PSP)、PTH 信使核糖核酸(mRNA)、 When hyperparathyroidism occurs, the cause of excessive replication of parathyroid cells and secretion of PTH remains unclear. 11 The deletion of chromosome tumor controller genes and evidence of monophyly were confirmed in some (30%) sporadic parathyroid adenoma studies; there was a report of primary familial parathyroid proliferation. Symptomatic patients find circulating mitotic factors, but the cause of most human parathyroid adenomas remains unexplained; similarly, the causes of proliferation of parathyroid cells caused by stimulation of patients with chronic renal failure are unclear. The authors of this study aimed to reveal the secretion of PTH from human parathyroid adenomas and the secretion of parathyroid hormone (PSP), PTH messenger RNA (mRNA),