种子细胞也是组织工程的核心研究内容,获得足够数量和质量的种子细胞是开展体外组织工程的必要基础。用于组织工程的种子细胞必须具有形成新组织结构的能力,主要来源于自体、同种异体或异种,在具体应用时各有利弊。一些成体干细胞由于不存在伦理争议以及发育分化条件相对简单等优势是重要的种子细胞,包括造血干细胞、骨髓干细胞、神经干细胞、脂肪干细胞、皮肤干细胞。人胚胎干细胞及其组织工程要真正在临床医学中得到应用,还有很长的一段路要走。其他一些细胞也可以作为组织工程种子细胞,包括内皮细胞、上皮细胞、成纤维细胞、骨细胞、成骨细胞、角质细胞、前脂肪细胞、脂肪细胞、肌腱细胞等。这些细胞已分化,分裂能力有限,但仍应用于组织工程。理想的种子细胞具有一定标准。 Seed cells are also the core research topics in tissue engineering. Obtaining a sufficient number and quality of seed cells is the necessary basis for conducting in vitro tissue engineering. Seed cells for tissue engineering must have the ability to form new organizational structures, mainly from autologous, allogenic or xenogenic, with advantages and disadvantages in each application. Some adult stem cells are important seed cells, including hematopoietic stem cells, bone marrow stem cells, neural stem cells, adipose-derived stem cells, and skin stem cells due to their lack of ethical controversy and their relative ease of development and differentiation. Human embryonic stem cells and their tissue engineering to be truly applied in clinical medicine, there is still a long way to go. Other cells can also be used as tissue engineered seed cells, including endothelial cells, epithelial cells, fibroblasts, osteocytes, osteoblasts, keratinocytes, preadipocytes, adipocytes, tendon cells and the like. These cells have been divided, the ability to divide is limited, but still applied to tissue engineering. The ideal seed cells have a certain standard.