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目的:探讨酒精性肝病(ALD)的危险因素及临床特点,寻找便捷的实验室指标,以便早期诊断。方法:回顾性分析我院167例ALD患者的住院病史,通过统计学分析其一般情况、饮酒史、临床表现及实验室指标。结果:ALD以40～60岁较多发;酒精性肝炎(AH)组患者日饮酒量较酒精性脂肪肝(AFL)组及酒精性肝硬化(AC)组大;AC组患者的饮酒时间较其他两组长;三组间实验室指标ALT、AST、AST/ALT、ALP、GGT、TBIL、ALB、PT比较差异有统计学意义。结论:ALD病情发展与饮酒史有关;对嗜酒者定期行AST、AST/ALT、GGT、TBIL、ALB、PT等生化指标监测,以争取早期诊断和治疗,改善预后。
Objective: To explore the risk factors and clinical features of alcoholic liver disease (ALD) and find convenient laboratory indexes for early diagnosis. Methods: A retrospective analysis of 167 hospitalized patients with ALD in our hospital history, statistical analysis of its general situation, history of alcohol consumption, clinical manifestations and laboratory indicators. Results: ALD was more frequent in patients aged 40-60 years. Alcohol consumption in alcoholic hepatitis (AH) group was higher than that in alcoholic fatty liver disease (AFL) group and alcoholic cirrhosis (AC) group. Alcohol consumption time in AC group was longer than that in other groups There were significant differences among the three groups in laboratory indexes ALT, AST, AST / ALT, ALP, GGT, TBIL, ALB, PT. CONCLUSIONS: The development of ALD is related to the history of alcohol consumption. The biochemical indexes such as AST, AST / ALT, GGT, TBIL, ALB and PT are regularly monitored in alcoholic patients for early diagnosis and treatment and prognosis.